The Tick-Borne Encephlitis Virus is endemic in an area ranging from northern China and Japan, through far-eastern Russia to Europe. TBEV is transmitted by the bite of infected ticks (Ixodes scapularis, Ixodes ricinus and Ixodes persulcatus), or (rarely) through the non-pasteurized milk of infected cows, sheeps and goats. TBE is a viral infectious disease involving the central nervous system (CNS). The disease is incurable once manifested, so there is no specific drug therapy for TBE. Sample Material Blood serum, plasma Cerebrospinal fluid Tick suspension sample Detection Channels FAM (495 – 520 nm) for Internal Control (IC) ROX (575 – 602 nm) for TBEV RNA